RESEARCH
Synthetic Nicotine Derivatives
Synthetic Nicotine Derivatives Synthetic nicotine is a manufactured form of nicotine, produced in a laboratory, as opposed to being extracted from tobacco leaves. Synthetic nicotine (tobacco-free nicotine) is chemically identical to natural nicotine (tobacco-derived nicotine) but is made in a laboratory using synthetic processes. Several synthetic derivatives of nicotine are being
Research: E-cigarettes
July 2026: Synthetic Cooling Agents in E-Cigarettes Actively Enhance Nicotine Reinforcement and Dopamine Signaling A recently published study is challenging a foundational assumption in the Electronic Nicotine Delivery Systems (ENDS) market. Researchers have discovered that synthetic cooling agents – most notably WS-3 and WS-23 – do far more than simply
Research: Nicotine Pouches
July 2026: Questions Raised Over ZYN Safety Review Following Former FDA Scientist’s Claims Questions have been raised over the safety review of Philip Morris International’s ZYN nicotine pouches after a former U.S. Food and Drug Administration (FDA) toxicologist alleged that the agency authorized the products without fully determining the composition
Research: Tobacco Products
October 2025: 70% of Policy Experts Misidentify Nicotine as Primary Cause of Smoking-related Diseases Based to a multi-market survey of 450 policy experts conducted across 15 different markets in 2024/25, British American Tobacco (BAT) stated that 70% of policy experts continue to misidentify nicotine as primary cause of smoking-related diseases.
Research: Cannabis
Cannabis potency Potency Monitoring Program, a project led by the US National Institute on Drug Abuse, reports that the average amount of tetrahydrocannabinol (THC: the plant’s main psychoactive component) in cannabis almost quadrupled over the last 25 years, mainly due to US growers selecting more potent strains. In the same
